Our new Apparent+ tissue clearing method is the sole strategy that delipidates samples without having improve in morphology and with minimal impact on structural integrity.
Megatome can be a vibrating microtome built to portion a broad range of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With large blade vibrating frequency and minimized blade deflection, Megatome allows substantial-throughput tissue sectioning with uniform area profile, and minimum tissue injury and knowledge decline.
Antibodies may perhaps take months to diffuse through just a few millimeters of tissue, using a steep labeling gradient from surface to core.
Megatome is suitable for accuracy: the blade vibrates at a better frequency and larger amplitude assortment than other microtomes, and includes a special deflection Handle mechanism.
SE employs a rotational electrical area to disperse remarkably electromobile molecules (for example antibodies or surfactant micelles) through a porous sample without having harmful electrically charged buildings throughout the tissue. This allows two-4 day clearing of intact organs,
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eFLASH can be a fast tissue labeling system that permits for uniform whole-organ staining in twenty rounds of labeling.
The SmartSPIM light sheet microscope delivers unparalleled resolution and acquisition speed all over intact tissue volumes, although its modular structure lets you upgrade and personalize individual components.
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Leverage the Crystal clear+ tissue clearing method, together with eFLASH and patented stochastic electrotransport technologies, to promptly apparent and label whole organs. Essential highlights and functions include:
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